AntibodyTargeted-Drug Conjugates 2015

13-15 April 2015, Crowne Plaza Porto, Porto, Portugal

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Day Three

Final Conference Programme | Wednesday 15th April 2015

SESSION 9:
ADC DEVELOPMENT III

Moderator: Kendall Morrison (Agensys Inc., Santa Monica, California, USA)

09.00-09.30
‘Synthetic biology and synthetic chemistry converge for novel antibody-drug conjugates’
Toni Kline, Kevin Yin, Krishna Bajjuri, Xiaofan Li, Alexander Steiner, Erik Zimmerman, Gang Yin, Tyler Heibeck, Venita DeAlmeida and Aaron Sato (Sutro Biopharma Inc., South San Francisco, California, USA)

09.30-10.00
‘Site-specific conjugation by Transglutaminase improves the therapeutic index of ADC in vivo
Florence Lhospice (Innate-Pharma SA, Marseille, France)

10.00-10.30
‘‘Bridge and click’ conjugation strategies: A new paradigm for the synthesis of porphyrin antibody-drug conjugates’
F. Bryden, A. Maruani, H. Savoie, V. Chudasama, M.E.B. Smith, S. Caddick and R.W. Boyle (University of Hull, Hull, UK)

10.30-11.00
Coffee Break & Posters

SESSION 10:
ADC DISCOVERY, EVALUATION & DEVELOPMENT

Moderator: Greg Bleck (Catalent Pharma Solutions, Somerset, New Jersey, USA)

11.00-11.30
‘Site restricted conjugation: The LinXis ADC alternative for native mAbs: The best of two worlds’
HendrikJan Houthoff, Guus van Dongen, Gerro van Rheenen, Paul Steverink, Joey Muns, Niels Sijbrandi and Dennis Waalboer (LinXis Pharmaceuticals, Breda The Netherlands)

11.30-12.00
‘High-affinity accumulation of a maytansinoid in cells via weak tubulin interaction’
Victor Goldmacher (ImmunoGen Inc, Waltham, Massachusetts, USA)

12.00-12.30
'A new biomarker to enhance the therapeutic index of Amanitin-based ADCs'
Andreas Pahl, Jan Anderl and Xiongbin Lu (Heidelberg Pharma GmbH, Ladenburg, Germany)

12.30-13.00
‘New workflow system for the design and evaluation of antibody drug conjugates (ADCs)’
Andreas Kaufmann (Genedata, Basel, Switzerland)

13.00-14.00
Lunch Break, Poster Breakdown & Departure

* This final programme is correct at the time of printing, however the organizers reserve the right to make any alterations that may be required in the interests and integrity of the final conference programme.

 

ATDC 2015 Sponsors

  • LinXis
  • NatureGeneTherapy.com
  • Nascent Biologics
  • Biovest
  • ImmunoGen
  • ADC Review
  • NBE Therapeutics
  • Sutro Biopharma
  • Genentech
  • Synthon
  • Aldevron
  • DNAvaccine.com
  • ONdrugDelivery
  • Catalent
  • Pfizer Oncology
  • Oncozine

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